DNA Health & Genetic Testing

Telomere Testing and Therapy

 

One of the greatest advances in preventive medicine is droppedimage_51here — a breakthrough science and technology that give us the ability to measure your biological age vs. your chronological age.

 

Forget about the number of years you’ve been on the planet. It’s all about telomeres—the sections of your DNA that cap off every chromosome.

These protective shoe-lace like ends prevent your chromosomes from fraying whenever cells replicate. They also control the way your cells repair and recover.

 

And they are one of the best molecular markers for aging. The long and short of your telomeres (literally) become a health barometer. The more “short” telomeres you have, the less healthy and the older you really are.

 

What’s affecting your telomere length? Plenty.

  • aging
  • stress
  • poor nutrition
  • being overweight
  • sedentary lifestyle

 

Your biological clock is ticking . . . what should you do? Start by having your telomeres tested with the most sophisticated measurement in the world— and it’s available right here at Cenegenics. Click Here for the complete brochure

Genetic Testing

 

Cenegenics is excited to announce a new partnership with New Amsterdam Genomics (NAG). NAG’s genomic testing is the most cutting-edge medical test available. This advanced DNA analysis will allow us to create an even more personalized, proactive program to get and keep you even healthier than before this technology was available.

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Cenegenics has chosen New Amsterdam for a variety of reasons. New Amsterdam uses what is referred to as Whole Exome Sequencing, the most clinically useful of the various types of genetic testing. NAG then cross-references 22,000 of your genes (essentially every gene in your body) with over 230,000 health-related findings.

 

NAG testing is also the most cost effective when considering the amount of information obtained, the reliability of results via supported research, and the personal support for you and your doctor to make the most of your results. Through a special arrangement with NAG, Cenegenics is able to offer this cutting edge testing for significantly lower price than others in the marketplace.

 

NAG has a very user-friendly portal to access results yourself if you chose. The portal presents your results in a variety of ways that make it much easier to make sense of your results. NAG has the fastest turnaround time in the industry in terms of getting your results back – just 4 weeks compared to others taking 16-20 weeks.

What Can I Learn From This Test?

Am I at risk of a serious medical condition such as heart disease, diabetes, or cancer?  How can I tailor my diet, exercise, and lifestyle choices to optimize my health?  Which medications and therapies are safest and most effective for me?

Cancer Risk

Risks of various cancers, 
coronary heart disease, heart rhythm irregularities, structural heart disease, high blood pressure, blood problems, diabetes, kidney function, respiratory problems, autoimmune diseases, stroke, eye problems, dementia, and neurodegenerative diseases.

Medication Responses

Medication responses, i.e. whether a person will metabolize a drug safely and whether that drug is likely to be effective in treating a particular problem.

Effects of Diet, Exercise, and Lifestyle

Effects of diet, exercise, and lifestyle, e.g. the effects of dietary fat, cholesterol, animal fat, saturated fat, and whole grains; abnormal sugar desire; the effects of caffeine, alcohol, and aspirin; vitamin deficiencies and altered metabolism; endurance markers; strength and power markers; muscle problems; optimal sport choices; and longevity markers.

Rare Genetic Disorders

Rare genetic disorders – the US government estimates 10% of the population has one.

Recessive Traits

Recessive traits a person may carry in their DNA that aren’t necessarily obvious or known. A very common example is sickle cell trait, but there are many others. This information can be useful for family planning.

Ancestry

Ancestry – your DNA is compared to 52 ethnicities from around the globe.

How will you and your doctor use the information?

There is a great deal of useful information any person (healthy or sick) can get from this type of genomic testing. You and your doctor can use these insights to structure a proactive care plan to get and keep you healthy. This analysis can help us:

 

  • Reduce your risk of, and possibly prevent certain health problems: By knowing what you are genetically at risk for, a more focused plan for prevention can be developed.
  • Discover which medicines may work best for you, and which ones you may want to avoid.
  • Optimize your nutrition and exercise:  You and your doctor can use the results to customize your exercise, nutrition and supplementation programs.
  • Testing may be helpful when trying to identify the cause of unusual symptoms.

 

According to NAG, 40% of people who complete their whole exome testing have a life changing result.

 

Your children, who share many of your genes, will benefit greatly from your test results. Results for you and your spouse may indicate a need for your children to get tested. Genetic counseling and/or family planning counseling may be appropriate.  NAG has a genetic counseling division specifically allocated for Cenegenics patients in need.

 

NAG has expert support personnel to help you and your doctor accurately interpret the results, and take appropriate action where necessary.

Why is Whole Exome Sequencing Better?

The exome is the entire protein-coding region of the human genome and includes over 22,000 genes. While comprising just 1% of our total DNA, the exome encompasses the vast majority of disease-causing mutations. By selectively targeting the exome, it gives your Cenegenics doctor the most effective and efficient genetic test for not only diagnosis and optimal treatment of existing problems, but actionable information to potentially prevent issues in the future.

 

Compared to genotyping (ex. 23andMe), whole exome sequencing provides a much broader view of your genetic information to better understand how your DNA affects your health.

 

In addition to the difference in how the sequencing is done, NAG uses far more sophisticated computer algorithms to scan the medical literature linking DNA variations you may have with published medical literature. This helps to make sense of, and determine the impact of even very rare mutations. The NAG database contains more than 200,000 associations between gene variations and health related findings — by far, the world’s largest. This database is continuously updated and correlated with your results.

What safeguards are in place to protect my privacy?

Encryption

  • All DNA information is encrypted while it is stored on hard drives and whenever it is transmitted between computers.

 

Who has access to my information?

  • The doctor ordering the testing has access to your information. You are also able to control which doctors have access to your data if data needs to be shared.
  • Results that have had personal information removed (de-identified) are shared with The Genomic Alliance to help advance genetic research
  • Otherwise, only certain authorized personnel within NAG have access to your data for quality control purposes.

 

Are life and health insurance companies allowed to ask me for this information?

  • Health insurance companies are not allowed to ask for this information and may not deny you coverage based on your results.
  • At this point, it is unclear if life insurance companies are allowed to ask for this information, and whether or not they can deny coverage or raise rates based on it.

 

Can someone discriminate against me because of my genomic information?

  • “The law forbids discrimination on the basis of genetic information when it comes to any aspect of employment, including hiring, firing, pay, job assignments, promotions, layoffs, training, fringe benefits, or any other term or condition of employment. An employer may never use genetic information to make an employment decision because genetic information is not relevant to an individual’s current ability to work.”

 

Portability

  • Your results always go with you even if you change doctors. The support from New Amsterdam continues as well.

Contact Dr. Singer via Cenegenics Park City.

Make an appointment with us today!